Common promoter variants of the NDUFV2 gene do not confer susceptibility to schizophrenia in Han Chinese

Table 1 Distribution of the NDUFV2 gene promoter variants in Han Chinese with and without schizophrenia

SNP and population	Genotype			P-value^a	Allele		P-value^a	HWE^b
	A/A (%)	A/G (%)	G/G (%)		A (%)	G (%)
rs6506640
SZ-HC (n = 529)	294 (55.6)	196 (37.0)	39 (7.4)	0.179	784 (74.1)	274 (25.9)	0.113	0.551
CT-HC (n = 505)	298 (59.0)	183 (36.2)	24 (4.8)		779 (77.1)	231 (22.9)		0.689
rs1156044
SZ-HC (n = 529)	292 (55.2)	195 (36.9)	42 (7.9)	0.142	779 (73.6)	279 (26.4)	0.075	0.396
CT-HC (n = 505)	299 (59.2)	180 (35.6)	26 (5.2)		778 (77.0)	232 (23.0)		0.914

Note: SZ = schizophrenia; HC = Han Chinese; CT = control
^a Two-tailed Fisher's Exact Probability Test was used to quantify the allele difference between the case and control groups
^b The Hardy-Weinberg Equilibrium was computed by Monte Carlo permutation test (10000 simulations)

ISSN: 1744-9081