DISC1 gene locus and linkage disequilibrium (LD) structure. (A) A diagram showing the exonic structure of DISC1 gene (black). The single nucleotide polymorphisms (SNPs) used in this study are shown in relation to the exons. (B) The linkage disequilibrium (LD) structure of the DISC1 region in the total autism samples according to Haploview (solid spine of LD, D'> 0.7). Markers with LD (D' < 1 and LOD > 2) are shown in red through pink (color intensity decreases with decreasing D' value). Regions of low LD (D' < 1 and LOD < 2) are shown in white. Two blocks were generated by Haploview.