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Table 2 Results of FBAT for the seven SNPs in DISC 1 gene

From: Evidence for association between Disrupted-in-schizophrenia 1 (DISC1) gene polymorphisms and autism in Chinese Han population: a family-based association study

Markers

Afreq

Families

S

E(s)

Z

p-values

rs4366301

C:0.831

G:0.169

169

169

213.00

125.00

233.00

105.00

-2.872

2.872

0.004

0.004

rs11585959

C:0.243

T:0.757

216

216

123.00

309.00

141.00

291.00

-2.199

2.199

0.028

0.028

rs1322784

G:0.369

A:0.631

242

242

206.00

278.00

202.50

281.50

-0.392

0.392

0.695

0.695

rs6668845

G:0.332

A:0.668

244

244

172.00

316.00

193.00

295.00

-2.326

2.326

0.020

0.020

rs10864698

A:0.330

G:0.670

242

242

175.00

309.00

191.50

292.50

-1.831

1.831

0.067

0.067

rs872624

G:0.345

A:0.655

232

232

168.00

296.00

180.00

284.00

-1.372

1.372

0.170

0.170

rs821616

A:0.881

T:0.119

130

130

186.00

74.00

181.50

78.50

0.728

-0.728

0.467

0.467

  1. FBAT, family-based association test; Afreq, allelic frequency; Families, number of informative families;
  2. S, test statistics for the observed number of transmitted alleles; E(S), expected value of S under the null hypothesis (i.e., no linkage or association).
  3. Significant p values (p < 0.05) are in boldface.