Skip to main content

Advertisement

Table 4 Results of the haplotype analysis using 2- or 3-markers sliding windows.

From: Association of the rs3743205 variant of DYX1C1 with dyslexia in Chinese children

Haplotypes Frequency Global tests Individual haplotype test Testing direct association using conditioning markers option
     p-values FDR (q-value) OR (95% CI) p-values p-values
2-markers rs8040756-rs3743205 A-G 0.123 0.0002 0.0033 Ref 0.6803 0.7814
   A-A 0.026    NA* 0.0005 rs3743205 as conditioning marker
   G-G 0.851    0.93(0.54 - 1.60) 0.2568  
  rs3743205-rs4255730 G-C 0.659 0.0073 0.0255 Ref 0.3972 0.7593
   G-T 0.315    0.94(0.65 - 1.38) 0.9244 rs3743205 as conditioning marker
   A-T 0.026    0.09(0.01 - 0.69) 0.0039  
  rs4255730-rs692646    NS    
  rs692646-rs692691 G-C 0.924 0.0118 0.0329 Ref 0.0555 0.0031 rs692691 as conditioning marker
   A-C 0.021    0.10(0.01 - 0.76) 0.0067 0.0232 rs692646 as conditioning marker
   A-T 0.055    0.78(0.35 - 1.78) 0.6831  
  rs692691-rs2290981    NS    
  rs2290981-rs4774768    NS    
  rs4774768-rs57809907    NS    
3-markers rs8040756-rs3743205-rs4255730 A-G-C 0.008 0.0019 0.0131 NA# 0.6099 rs3743205 as conditioning marker
   A-G-T 0.110    0.99(0.56 - 1.77) 0.1828  
   A-A-T 0.024    NA* 0.0009  
   G-G-C 0.654    Ref 0.3361  
   G-G-T 0.204    0.87(0.55 - 1.36) 0.7459  
  rs3743205-rs4255730-rs692646    NS    
  rs4255730-rs692646-rs692691    NS    
  rs692646-rs692691-rs2290981    NS    
  rs692691-rs2290981-rs4774768    NS    
  rs2290981-rs4774768- rs57809907    NS    
  1. NS = Not significant.
  2. Ref = Reference haplotype,
  3. NA* = OR calculation was not performed when zero value present in contingency table
  4. NA# = individual haplotype frequency was below 1% in the samples.