Association of the rs3743205 variant of DYX1C1 with dyslexia in Chinese children

Table 4 Results of the haplotype analysis using 2- or 3-markers sliding windows.

Haplotypes			Frequency	Global tests		Individual haplotype test		Testing direct association using conditioning markers option
				p-values	FDR (q-value)	OR (95% CI)	p-values	p-values
2-markers	rs8040756-rs3743205	A-G	0.123	0.0002	0.0033	Ref	0.6803	0.7814
		A-A	0.026			NA*	0.0005	rs3743205 as conditioning marker
		G-G	0.851			0.93(0.54 - 1.60)	0.2568
	rs3743205-rs4255730	G-C	0.659	0.0073	0.0255	Ref	0.3972	0.7593
		G-T	0.315			0.94(0.65 - 1.38)	0.9244	rs3743205 as conditioning marker
		A-T	0.026			0.09(0.01 - 0.69)	0.0039
	rs4255730-rs692646			NS
	rs692646-rs692691	G-C	0.924	0.0118	0.0329	Ref	0.0555	0.0031 rs692691 as conditioning marker
		A-C	0.021			0.10(0.01 - 0.76)	0.0067	0.0232 rs692646 as conditioning marker
		A-T	0.055			0.78(0.35 - 1.78)	0.6831
	rs692691-rs2290981			NS
	rs2290981-rs4774768			NS
	rs4774768-rs57809907			NS
3-markers	rs8040756-rs3743205-rs4255730	A-G-C	0.008	0.0019	0.0131	NA^#		0.6099 rs3743205 as conditioning marker
		A-G-T	0.110			0.99(0.56 - 1.77)	0.1828
		A-A-T	0.024			NA*	0.0009
		G-G-C	0.654			Ref	0.3361
		G-G-T	0.204			0.87(0.55 - 1.36)	0.7459
	rs3743205-rs4255730-rs692646			NS
	rs4255730-rs692646-rs692691			NS
	rs692646-rs692691-rs2290981			NS
	rs692691-rs2290981-rs4774768			NS
	rs2290981-rs4774768- rs57809907			NS

NS = Not significant.
Ref = Reference haplotype,
NA* = OR calculation was not performed when zero value present in contingency table
NA# = individual haplotype frequency was below 1% in the samples.

ISSN: 1744-9081