Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B & NTRK2 polymorphisms

Table 2 Association of candidate markers

Gene Symbol	Allele	RS number	Significance (p)
			Allelic	Genotypic
SLC1A3	C/T	rs2269272	0.562	0.075
HTR1B	C/G	rs6296	0.895	0.047
SLC1A2	G/C	rs4755404	0.024	0.069
COMT	G/A	rs4680	0.123	0.205
HTR2A	G/A	rs6313	0.696	0.568
	C/T	rs6311	0.628	0.307
HTR1A	C/G	rs6295	0.714	0.907
TPH1	G/T	rs1799913	0.136	0.192
	G/T	rs1800532	0.136	0.192
TPH2	A/G	rs7305115	0.647	0.559
DBH	T/C	rs2519152	0.377	0.761
CNR1	T/G	rs6454674	0.948	0.986
	T/C	rs806368	0.695	0.885
	G/A	rs6801844	0.883	0.612
BDNF	C/T	rs6265	0.422	0.650
ABCG1	A/G	rs1044317	0.261	0.397
	C/G	rs225374	0.631	0.823
	C/G	rs914189	0.862	0.986
GABRG2	C/A	rs211014	0.398	0.180
GABRB2	A/G	rs1816072	0.270	0.276
	C/T	rs2491397	0.310	0.594
NTRK2	A/G	rs1659400	0.453	0.474
	G/A	rs1187272	0.137	0.388
CRHR1	A/G	rs110402	0.805	0.763
	T/G	rs242924	0.935	0.463
	C/T	rs7209436	0.852	0.872
MAOA	T/G	rs1799835	NA	NA
GABRA5	A/G	rs140681	NA	NA

P value obtained from Pearson's Chi-square test or Fisher's exact test. NA = not applicable, as genotype are identical for case and controls.

ISSN: 1744-9081