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Table 3 Genotype frequencies and genetic models of association

From: Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B & NTRK2 polymorphisms

   

Genotype Frequencies

 

Significance (p value)

 

Gene symbol

RS number

Genotype

Controls

SA cases

Additive

Dominant

Over-Dominant

Recessive

SLC1A3

rs2269272

CC/CT/TT

0.687/0.229/0.084

0.667/0.32/0.013

0.56

0.787

0.199

0.042

HTR1B

rs6296

GG/CG/CC

0.59/0.265/0.145

0.5/0.432/0.068

0.847

0.256

0.028

0.121

SLC1A2

rs4755404

CC/CG/GG

0.451/0.427/0.122

0.28/0.52/0.20

0.029

0.026

0.243

0.182

  1. P value obtained from Pearson's Chi-square test for all genotype tests, with the exception of the additive model, where an exact Armitage trend test was used. Numbers highlighted in bold represent genotype models that were significantly associated with Suicide attempt status (P = < 0.05). SA: Suicide Attempt.
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Behavioral and Brain Functions

ISSN: 1744-9081

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