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Table 4 Final gene by gene interaction model: Logistic regression analysis

From: Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B & NTRK2 polymorphisms

       

95% C.I for OR

Variable

B

S.E

Wald

df

P value

OR

Lower

Upper

Age

-.043

.015

8.305

1

.004

.958

.930

.986

Sex

-1.062

.422

6.349

1

.012

.346

.151

.790

alcohol abuse/dependence

1.164

.422

7.598

1

.006

3.204

1.400

7.333

schizophrenia and other psychotic disorders

- 0.139

.810

.029

1

.864

.870

.178

4.257

rs6296

1.104

.868

1.615

1

.204

3.015

.550

16.539

rs4755404

1.291

.593

4.736

1

.030

3.636

1.137

11.628

rs1659400

.953

.934

1.041

1

.308

2.592

.416

16.159

rs6296 by rs4755404

-1.141

1.065

1.150

1

.284

.319

.040

2.573

rs6296 by rs1659400

-1.356

1.440

.887

1

.346

.258

.015

4.332

rs1659400 by rs4755404

-2.060

1.139

3.275

1

.070

.127

.014

1.187

rs6296 by rs4755404 by rs1659400

3.613

1.811

3.982

1

.046

37.087

1.067

1289.592

Constant

.592

.778

.579

1

.447

1.808

  
  1. B, unstandardised logistic regression coefficient; S.E, Standard error; Wald, Wald statistic; df, Degrees of freedom; OR, Odds ratio; C.I., Confidence interval