Skip to main content

Table 1 Association analysis of the 5 SNPs in both genders combined

From: Possible association between Interleukin-1beta gene and schizophrenia in a Japanese population

    Males
SNP name Allele 1/2   N Genotype Allele P-value HWE P-value
     1/1 1/2 2/2 1 2 Genotype Allele  
rs2853550 A/G Schizophrenia 531 9 128 394 146 916 0.23 0.088 0.86
     (0.02) (0.24) (0.74) (0.14) (0.86)    
   Controls 1115 14 232 869 260 1970    0.88
     (0.01) (0.21) (0.78) (0.12) (0.88)    
rs1143634 A/G Schizophrenia 525 1 41 483 43 1007 0.97(a) 0.90 0.59
     (0.00) (0.08) (0.92) (0.04) (0.96)    
   Controls 1121 2 90 1029 94 2148 1.00   
     (0.00) (0.08) (0.92) (0.04) (0.96)    
rs1143633 C/T Schizophrenia 524 111 249 164 471 577 0.035 0.0089 0.38
     (0.21) (0.48) (0.31) (0.45) (0.55)    
   Controls 1123 188 525 410 901 1345    0.38
     (0.17) (0.47) (0.37) (0.40) (0.60)    
rs1143630 T/G Schizophrenia 520 13 140 367 166 874 0.88 0.66 1.00
     (0.03) (0.27) (0.71) (0.16) (0.84)    
   Controls 1119 24 296 799 344 1894    0.65
     (0.02) (0.26) (0.71) (0.15) (0.85)    
rs16944 A/G Schizophrenia 521 123 253 145 499 543 0.18 0.060 0.54
     (0.24) (0.49) (0.28) (0.48) (0.52)    
   Controls 1111 226 534 351 986 1236    0.39
     (0.20) (0.48) (0.32) (0.44) (0.56)    
  1. (a) Calculated using Fisher's exact test.
  2. SNP: single nucleotide polymorphism; HWE: Hardy-Weinberg Disequilibrium
  3. Numbers in parentheses represent the frequencies of genotypes and alleles.