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Table 1 Association analysis of the 5 SNPs in both genders combined

From: Possible association between Interleukin-1beta gene and schizophrenia in a Japanese population

   

Males

SNP name

Allele 1/2

 

N

Genotype

Allele

P-value

HWE P-value

    

1/1

1/2

2/2

1

2

Genotype

Allele

 

rs2853550

A/G

Schizophrenia

531

9

128

394

146

916

0.23

0.088

0.86

    

(0.02)

(0.24)

(0.74)

(0.14)

(0.86)

   
  

Controls

1115

14

232

869

260

1970

  

0.88

    

(0.01)

(0.21)

(0.78)

(0.12)

(0.88)

   

rs1143634

A/G

Schizophrenia

525

1

41

483

43

1007

0.97(a)

0.90

0.59

    

(0.00)

(0.08)

(0.92)

(0.04)

(0.96)

   
  

Controls

1121

2

90

1029

94

2148

1.00

  
    

(0.00)

(0.08)

(0.92)

(0.04)

(0.96)

   

rs1143633

C/T

Schizophrenia

524

111

249

164

471

577

0.035

0.0089

0.38

    

(0.21)

(0.48)

(0.31)

(0.45)

(0.55)

   
  

Controls

1123

188

525

410

901

1345

  

0.38

    

(0.17)

(0.47)

(0.37)

(0.40)

(0.60)

   

rs1143630

T/G

Schizophrenia

520

13

140

367

166

874

0.88

0.66

1.00

    

(0.03)

(0.27)

(0.71)

(0.16)

(0.84)

   
  

Controls

1119

24

296

799

344

1894

  

0.65

    

(0.02)

(0.26)

(0.71)

(0.15)

(0.85)

   

rs16944

A/G

Schizophrenia

521

123

253

145

499

543

0.18

0.060

0.54

    

(0.24)

(0.49)

(0.28)

(0.48)

(0.52)

   
  

Controls

1111

226

534

351

986

1236

  

0.39

    

(0.20)

(0.48)

(0.32)

(0.44)

(0.56)

   
  1. (a) Calculated using Fisher's exact test.
  2. SNP: single nucleotide polymorphism; HWE: Hardy-Weinberg Disequilibrium
  3. Numbers in parentheses represent the frequencies of genotypes and alleles.