Behavioral and Brain Functions

Table 2 Association analysis of the 5 SNPs in males

From: Possible association between Interleukin-1beta gene and schizophrenia in a Japanese population

			Males
SNP name	Allele 1/2		N	Genotype			Allele		P-value		HWE P-value
				1/1	1/2	2/2	1	2	Genotype	Allele
rs2853550	A/G	Schizophrenia	300	4	74	222	82	518	0.68^(a)	0.69	0.62
				(0.01)	(0.25)	(0.74)	(0.14)	(0.86)
		Controls	383	7	85	291	99	667			0.82
				(0.02)	(0.22)	(0.76)	(0.13)	(0.87)
rs1143634	A/G	Schizophrenia	298	0	24	274	24	572	0.81^(a)	0.82	1.00
				(0.00)	(0.08)	(0.92)	(0.04)	(0.96)
		Controls	383	1	27	355	29	737			0.42
				(0.00)	(0.07)	(0.93)	(0.04)	(0.96)
rs1143633	C/T	Schizophrenia	299	59	145	95	263	335	0.43	0.47	0.81
				(0.20)	(0.48)	(0.32)	(0.44)	(0.56)
		Controls	383	77	168	138	322	444			0.059
				(0.20)	(0.44)	(0.36)	(0.42)	(0.58)
rs1143630	T/G	Schizophrenia	295	7	81	207	95	495	0.75	0.73	1.00
				(0.02)	(0.27)	(0.70)	(0.16)	(0.84)
		Controls	383	6	106	271	118	648			0.32
				(0.02)	(0.28)	(0.71)	(0.15)	(0.85)
rs16944	A/G	Schizophrenia	295	66	143	86	275	315	0.92	0.67	0.64
				(0.22)	(0.48)	(0.29)	(0.47)	(0.53)
		Controls	385	82	186	117	350	420			0.61
				(0.21)	(0.48)	(0.30)	(0.45)	(0.55)

(a) Calculated using Fisher's exact test.
SNP: single nucleotide polymorphism; HWE: Hardy-Weinberg Disequilibrium
Numbers in parentheses represent the frequencies of genotypes and alleles.

Back to article page

ISSN: 1744-9081

Contact us

Submission enquiries: journalsubmissions@springernature.com