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Table 2 Dopamine clearance parameters in rat striatum

From: Maternal separation affects dopamine transporter function in the Spontaneously Hypertensive Rat: An in vivo electrochemical study

 

Amplitude (μM)

k-1

T rise (s)

T50 (s)

T80 (s)

T100 (s)

 

Mean ± SEM

Median

Lower quartile

Upper quartile

Median

Lower quartile

Upper quartile

Median

Lower quartile

Upper quartile

Median

Lower quartile

Upper quartile

Median

Lower quartile

Upper quartile

WKY NMS

1.1187 ± 0.0320

0.0025

0.0017

0.0041

3.00

2.00

4.00

6.00

4.00

9.00

9.00

7.00

16.00

43.00

27.00

69.00

WKY MS

1.1777 ± 0.0342

0.0018

0.0008

0.0109

3.00

2.00

7.00

4.50

3.00

10.67

8.50

4.00

23.17

26.00

8.17

93.50

SHR NMS

1.1653 ± 0.0469

0.0036

0.0016

0.0078

2.00

2.00

4.67

6.00

3.33

7.33

11.00

7.00

16.00

33.00

16.00

39.33

SHR MS

1.1407 ± 0.0354

0.0015

0.0007

0.0039

3.00

2.00

6.00

7.00

4.00

15.00

16.00

6.00

40.00

48.00

21.00

110.66

  1. * Amplitudes of dopamine peaks were normally distributed, while k-1, T rise, T50, T80 and T100 data were non-normally distributed (Shapiro-Wilks test). k-1 is the first-order rate constant of dopamine decay versus time. T rise represents the time taken for the dopamine concentration to reach the peak value. T50 represents the time taken for the dopamine concentration to return from peak amplitude to 50% of peak value. T80 represents the time taken for the dopamine concentration to return from peak amplitude to 20% of peak value. T100 represents the time taken for the dopamine concentration to return from peak amplitude to the baseline value prior to the ejection of dopamine