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Table 2 Genotype Association of COMT SNP rs165774

From: A novel SNP in COMT is associated with alcohol dependence but not opiate or nicotine dependence: a case control study

Sample Genotype Counts   p-value*
  AA (%) AG (%) GG (%)  
control 39 (16.25) 98 (40.83) 103 (42.92)  
Nicotine dependence 21 (14.38) 51 (34.93) 74 (50.69) 0.330
Odds ratio 1 0.966 1.334 0.205
p-value   1.000 0.700  
Opiate dependence 13 (11.11) 47 (40.17) 57 (48.72) 0.363
Odds ratio 1 1.439 1.660 0.172
p-value   0.626 0.300  
Alcohol dependence 18 (7.96) 97 (42.92) 111(49.12) 0.022
Odds ratio 1 2.146 2.336 0.023
p-value   0.029 0.012  
  1. * p-value determined by Pearson's χ2 test (DF = 2)
  2. p-value determined using the extended Mantel-Haenszel test for trend (DF = 1)