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Figure 4 | Behavioral and Brain Functions

Figure 4

From: Impulsiveness, overactivity, and poorer sustained attention improve by chronic treatment with low doses of l-amphetamine in an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD)

Figure 4

This figure shows the mean within-session effects of l-amphetamine on sustained attention. Left panel: Sessions 31 through 44, baseline sessions. The three SHR subgroups are closely similar, so are the three WKY subgroups, prior to the injection program. Middle panel: Sessions 45 through 58, treatment sessions. Both doses improve SHR behavior. Right panel: Sessions 59 through 61, post-treatment sessions. The SHR subgroups return to pre-drug levels. The 2.2 mg/kg WKY subgroup apparently got worse following drug exposure. The WKY performance appears unaltered from pre- to post-treatment days. The groups that had received saline during sessions 45 through 58, now received 2.2 mg/kg.

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