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Figure 5 | Behavioral and Brain Functions

Figure 5

From: Impulsiveness, overactivity, and poorer sustained attention improve by chronic treatment with low doses of l-amphetamine in an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD)

Figure 5

This figure shows the mean within-session effects of l-amphetamine on activity. Left panel: Sessions 31 through 44, baseline sessions. The three SHR subgroups are closely similar, so are the three WKY subgroups, prior to the injection program. Middle panel: Sessions 45 through 58, treatment sessions. 2.2 mg/kg reduces SHR overactivity. Right panel: Sessions 59 through 61, post-treatment sessions. The 2.2 mg/kg SHR subgroup returns to pre-drug levels. The WKY subgroups are apparently unaffected by the drug. The subgroups that had received saline during sessions 45 through 58, now received 2.2 mg/kg.

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