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Figure 6 | Behavioral and Brain Functions

Figure 6

From: Impulsiveness, overactivity, and poorer sustained attention improve by chronic treatment with low doses of l-amphetamine in an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD)

Figure 6

This figure shows the mean within-session effects of l-amphetamine. Left panel: Sessions 31 through 44, baseline sessions. The three SHR subgroups are closely similar, so are the three WKY subgroups, prior to the injection program. Middle panel: Sessions 45 through 58, treatment sessions. The 2.2 mg/kg dose reduced SHR impulsiveness. Right panel: Sessions 59 through 61, post-treatment sessions. The 2.2 mg/kg SHR subgroup returned to pre-drug levels. The 2.2 mg/kg WKY subgroup apparently got worse following drug exposure. The subgroups that had received saline during sessions 45 through 58, now received 2.2 mg/kg l-amphetamine.

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