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Table 2 Comparison of genotype and allele frequencies of six SNPs at the NRXN1 gene between schizophrenic patients and healthy control subjects

From: A case-control association study of NRXN1 polymorphisms with schizophrenia in Chinese Han population

Makers Genotype N (Freq.) Chi-square (df = 2) p- value HWEP Allele N (Freq.) Chi-square (df = 1) p- value OR (95% CI)
rs10490168 AA AG GG     A G    
Cases 10(0.013) 173(0.225) 585(0.762) 6.049 0.048 0.485 193(0.126) 1343(0.874) 5.677 0.017 0.78(0.63-0.96)
Controls 13(0.018) 204(0.276) 521(0.706)    0.168 230(0.156) 1246(0.844)    
rs2024513 AA AG GG     A G    
Cases 544(0.708) 206(0.268) 18(0.023) 7.521 0.023 0.772 1294(0.842) 242(0.158) 7.327 0.006 1.30(1.07-1.56)
Controls 480(0.650) 228(0.309) 30(0.041)    0.655 1188(0.805) 288(0.195)    
rs10174398 CC CT TT     C T    
Cases 276(0.359) 359(0.467) 133(0.173) 0.727 0.695 0.382 911(0.593) 625(0.407) 1.064 0.397 1.06(0.92-1.23)
Controls 254(0.344) 345(0.467) 139(0.188)    0.256 853(0.578) 623(0.422)    
rs10195460 AA AG GG     A G    
Cases 61(0.079) 318(0.414) 389(0.507) 1.197 0.549 0.721 440(0.286) 1096(0.714) 0.972 0.323 0.92(0.79-1.08)
Controls 62(0.084) 323(0.438) 353(0.478)    0.321 447(0.303) 1029(0.697)    
rs13382584 CC CT TT     C T    
Cases 14(0.018) 200(0.260) 554(0.721) 7.075 0.029 0.404 228(0.148) 1308(0.852) 6.821 0.009 0.77(0.64-0.94)
Controls 23(0.031) 225(0.305) 489(0.664)    0.638 271(0.184) 1203(0.816)    
rs1558852 AA AG GG     A G    
Cases 234(0.305) 383(0.499) 151(0.197) 4.666 0.097 0.799 851(0.554) 685(0.446) 4.627 0.031 0.85(0.74-0.99)
Controls 259(0.351) 357(0.484) 122(0.165)    0.956 875(0.593) 601(0.407)    
  1. Freq., frequency; HWEP: the p-value for Hardy-Weinberg equilibrium tests; OR, odds ratio; CI, confidence interval.