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Table 1 Studies examining effects of methylphenidate on attentional set-shifting tests in children with ADHD or animal models

From: Effects of methylphenidate on attentional set-shifting in a genetic model of attention-deficit/hyperactivity disorder

Citation Dose Time Outcome Subjects
[16] 0.5 mg/kg acute positive effects of ED Children with ADHD
[25] 0.25 mg/kg 0.5 mg/kg 6 days performance were enhanced at a low dose while worsened at a moderate dose of ED Children with ADHD
[26] 0.3 mg/kg 0.6 mg/kg acute no change Children with ADHD
[27] 35 mg/day no information positive effects of ED Children with ADHD
[28] 0.3 mg/kg 0.6 mg/kg 4 weeks no change Children with ADHD
[6] 1.5 mg/kg 28 days positive effects of ID and ED SHR