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Table 1 Studies examining effects of methylphenidate on attentional set-shifting tests in children with ADHD or animal models

From: Effects of methylphenidate on attentional set-shifting in a genetic model of attention-deficit/hyperactivity disorder

Citation

Dose

Time

Outcome

Subjects

[16]

0.5 mg/kg

acute

positive effects of ED

Children with ADHD

[25]

0.25 mg/kg

0.5 mg/kg

6 days

performance were enhanced at a low dose while worsened at a moderate dose of ED

Children with ADHD

[26]

0.3 mg/kg

0.6 mg/kg

acute

no change

Children with ADHD

[27]

35 mg/day

no information

positive effects of ED

Children with ADHD

[28]

0.3 mg/kg

0.6 mg/kg

4 weeks

no change

Children with ADHD

[6]

1.5 mg/kg

28 days

positive effects of ID and ED

SHR