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Table 2 Genotype and allele frequencies of four SNPs in GHRL gene between schizophrenia patients and healthy controls

From: Association between Ghrelin gene (GHRL) polymorphisms and clinical response to atypical antipsychotic drugs in Han Chinese schizophrenia patients

Marker N a Genotype b HWE P-value Allele b P-value ORc (95%CI)
rs696217   GG GT TT    G T   
Patients 634 427(0.684) 180(0.288) 17(0.027) 0.704 0.649 1034(0.829) 214(0.171) 0.773 1.03(0.83-1.27)
Controls 606 400(0.670) 184(0.308) 13(0.022) 0.123   984(0.824) 210(0.176)   
rs26802   AA AC CC    A C   
Patients 634 534(0.842) 95(0.150) 5(0.008) 0.732 0.944 1163(0.917) 105(0.083) 0.922 1.01(0.76-1.35)
Controls 606 505(0.839) 93(0.154) 4(0.007) 0.900   1103(0.916) 101(0.084)   
rs27647   AA AG GG    A G   
Patients 634 10(0.016) 133(0.210) 491(0.774) 0.773 0.410 153(0.121) 1115(0.879) 0.301 1.13(0.88-1.46)
Controls 606 5(0.008) 120(0.198) 480(0.793) 0.400   130(0.107) 1080(0.893)   
rs26311   CC CG GG    C G   
Patients 634 253(0.402) 298(0.474) 78(0.124) 0.498 0.826 804(0.639) 454(0.361) 0.723 1.03(0.87-1.21)
Controls 606 234(0.387) 297(0.491) 74(0.122) 0.171   765(0.632) 445(0.368)   
  1. a Number of samples which are well genotyped
  2. b Frequencies are shown in parenthesis
  3. c Odds ratios of alleles were calculated for each reference vs. variant allele