Table 2 Genotype and allele frequencies of four SNPs in GHRL gene between schizophrenia patients and healthy controls
Marker | N a | Genotype b | HWE | P-value | Allele b | P-value | ORc (95%CI) | |||
|---|---|---|---|---|---|---|---|---|---|---|
rs696217 | Â | GG | GT | TT | Â | Â | G | T | Â | Â |
Patients | 634 | 427(0.684) | 180(0.288) | 17(0.027) | 0.704 | 0.649 | 1034(0.829) | 214(0.171) | 0.773 | 1.03(0.83-1.27) |
Controls | 606 | 400(0.670) | 184(0.308) | 13(0.022) | 0.123 | Â | 984(0.824) | 210(0.176) | Â | Â |
rs26802 | Â | AA | AC | CC | Â | Â | A | C | Â | Â |
Patients | 634 | 534(0.842) | 95(0.150) | 5(0.008) | 0.732 | 0.944 | 1163(0.917) | 105(0.083) | 0.922 | 1.01(0.76-1.35) |
Controls | 606 | 505(0.839) | 93(0.154) | 4(0.007) | 0.900 | Â | 1103(0.916) | 101(0.084) | Â | Â |
rs27647 | Â | AA | AG | GG | Â | Â | A | G | Â | Â |
Patients | 634 | 10(0.016) | 133(0.210) | 491(0.774) | 0.773 | 0.410 | 153(0.121) | 1115(0.879) | 0.301 | 1.13(0.88-1.46) |
Controls | 606 | 5(0.008) | 120(0.198) | 480(0.793) | 0.400 | Â | 130(0.107) | 1080(0.893) | Â | Â |
rs26311 | Â | CC | CG | GG | Â | Â | C | G | Â | Â |
Patients | 634 | 253(0.402) | 298(0.474) | 78(0.124) | 0.498 | 0.826 | 804(0.639) | 454(0.361) | 0.723 | 1.03(0.87-1.21) |
Controls | 606 | 234(0.387) | 297(0.491) | 74(0.122) | 0.171 | Â | 765(0.632) | 445(0.368) | Â | Â |