Figure 1

Experimental design. Group 1 (n = 10 control and n = 14 CRS-exposed for saccharin preference and quinine aversion; body and organ weight analysis performed in n = 8 for control versus CRS). Group 2 (for HCS, n = 8 control and n = 9 CRS-exposed; n = 8 control and n = 8 CRS-exposed for TST, FST and EZM). Group 3 (n = 6 Control and CRS-exposed). Group 4 (n = 12 Control and n = 16 CRS-exposed; CRS group further divided, n = 8 saline and n = 8 phenserine). For cFos immunohistochemistry (IHC) experiment control group further divided into n = 6 water exposure and n = 6 urine exposure; n = 6 saline/CRS/urine exposure and n = 6 phenserine/CRS/urine exposure were analyzed.