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Table 2 Genotype distribution and frequency of the 5HTTLPR and 5HT1B G861C polymorphism

From: Interaction between Serotonin Transporter and Serotonin Receptor 1 B genes polymorphisms may be associated with antisocial alcoholism

Group

n

5HTTLPR genotype frequency (%)

χ²

P-value

5HT1B G861C genotype frequency (%)

χ²

P-value

S/S, S/L G , L G /L G

S/L A , L G /L A , L A /L A , S/XL, L A /XL, L G /XL

G/G

G/C

C/C

AS-ALC

120

90 (75.0)

30 (25.0)

5.39

0.02a*

25 (20.8)

70 (58.3)

25 (20.8)

4.58

0.10a

AS-N-ALC

153

100 (65.4)

53 (34.6)

2.95

0.09b

44 (28.8)

74 (48.4)

35 (22.9)

3.07

0.22b

Controls

191

119 (62.3)

72 (37.7)

5.50

0.06c

55 (28.8)

88 (46.1)

48 (25.1)

5.04

0.28c

  1. AS-ALC: Antisocial alcoholism;
  2. AS-N-ALC: Antisocial personality disorder without alcoholism.
  3. a AS-ALC vs. Healthy Controls.
  4. b AS-ALC vs. AS-N-ALC.
  5. c AS-ALC vs. AS-N-ALC vs. Controls.
  6. *P < 0.05.