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Table 2 Genotype distribution and frequency of the 5HTTLPR and 5HT1B G861C polymorphism

From: Interaction between Serotonin Transporter and Serotonin Receptor 1 B genes polymorphisms may be associated with antisocial alcoholism

Group n 5HTTLPR genotype frequency (%) χ² P-value 5HT1B G861C genotype frequency (%) χ² P-value
S/S, S/L G , L G /L G S/L A , L G /L A , L A /L A , S/XL, L A /XL, L G /XL G/G G/C C/C
AS-ALC 120 90 (75.0) 30 (25.0) 5.39 0.02a* 25 (20.8) 70 (58.3) 25 (20.8) 4.58 0.10a
AS-N-ALC 153 100 (65.4) 53 (34.6) 2.95 0.09b 44 (28.8) 74 (48.4) 35 (22.9) 3.07 0.22b
Controls 191 119 (62.3) 72 (37.7) 5.50 0.06c 55 (28.8) 88 (46.1) 48 (25.1) 5.04 0.28c
  1. AS-ALC: Antisocial alcoholism;
  2. AS-N-ALC: Antisocial personality disorder without alcoholism.
  3. a AS-ALC vs. Healthy Controls.
  4. b AS-ALC vs. AS-N-ALC.
  5. c AS-ALC vs. AS-N-ALC vs. Controls.
  6. *P < 0.05.