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Table 4 Effect of orally SA administration for 7 days in biochemical parameters of rat brain antioxidant status

From: Brain antioxidant markers, cognitive performance and acetylcholinesterase activity of rats: efficiency of Sonchus asper

Treatment

Catalase (U/min)

Superoxide dismutase (U/mg protein)

Glutathione peroxidase assay (nmol/mg protein)

Glutathione reductase (nmol/min

/mg protein)

Glutathione-S-transferase (nmol/min

/mg protein)

Reduced glutathione (ÎĽmol/g tissue)

Thiobarbituric acid reactive substances (nmol/min

/ mg protein)

Control

11.0 ± 0.25

7.18 ± 2.8

43.3 ± 3.58

174.5 ± 20.7

115.8 ± 26.11

64.5 ± 10.7

184.5 ± 8.7

SA50

15.5 ± 2.8*

13.5 ± 1.4**

55.3 ± 1.85*

203.3 ± 10.3**

139.8 ± 13.3 *

88.0 ± 8.3*

200.3 ± 7.3*

SA100

14.0 ± 1.12*

18.3 ± 1.7 **

65.3 ± 5.14**

218.0 ± 10.5 **

150.8 ± 11.5**

91.8 ± 10.0**

208.0 ± 10.0**

  1. * p < 0.05 significant difference from control littermates (n = 10/group)
  2. ** p < 0.01 significant difference from control littermates (n = 10/group)
  3. The rats brain biochemical parameters are expressed as mean ± S.E.M values