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Table 1 Clinical characteristics of case–control samples

From: Variation in regulator of G-protein signaling 17 gene (RGS17) is associated with multiple substance dependence diagnoses

  African Americans (AAs) European American (EAs)
  SD cases (n = 1,562) Contols (n = 343) SD cases (n = 981) Contols (n = 351)
AD, n (%) 1064 (68.1%) 0 (0%) 671 (68.4%) 0 (0%)
CD, n (%) 1309 (83.8%) 0 (0%) 696 (70.9%) 0 (0%)
OD, n (%) 358 (22.9%) 0 (0%) 577 (58.8%) 0 (0%)
MjD, n (%) 531 (34.0%) 0 (0%) 318 (32.4%) 0 (0%)
AD + CD + OD + MjD, n(%) 87 (5.6%) 0 (0%) 131 (13.4%) 0 (0%)
AD + CD + OD, n(%) 196 (12.5%) 0 (0%) 283 (28.8%) 0 (0%)
AD + OD + MjD, n(%) 90 (5.8%) 0 (0%) 141 (14.4%) 0 (0%)
AD + CD + MjD, n(%) 360 (23.0%) 0 (0%) 195 (19.9%) 0 (0%)
CD + OD + MjD, n(%) 116 (7.4%) 0 (0%) 182 (18.6%) 0 (0%)
AD + CD, n(%) 854 (54.7%) 0 (0%) 476 (48.5%) 0 (0%)
AD + OD, n(%) 217 (13.9%) 0 (0%) 321 (32.7%) 0 (0%)
AD + MjD, n(%) 424 (27.1%) 0 (0%) 232 (23.6) 0 (0%)
CD + OD, n(%) 303 (19.4%) 0 (0%) 436 (44.4%) 0 (0%)
CD + MjD, n(%) 454 (29.1%) 0 (0%) 260 (26.5%) 0 (0%)
OD + MjD, n(%) 123 (7.9%) 0 (0%) 206 (21.0%) 0 (0%)
Male, n (%) 786 (50.5%) 153 (44.6%) 485 (49.4%) 190 (54.1%)
  χ2 = 3.45, df = 1, P = 0.063   χ2 = 1.70, df = 1, P = 0.192  
Age, years 39 ± 9 39 ± 9 38 ± 12 41 ± 13
  t = −1.029, P = 0.304 (2-tailed)   t = 4.76, P = 2.2 × 10-6 (2-tailed)  
  1. SD, substance (alcohol, cocaine, opioid, and/or marijuana) dependence.
  2. AD, alcohol dependence; CD, cocaine dependence; OD, opioid dependence; MjD, marijuana dependence.
  3. Symbol " + " means comorbidity.
  4. Sex differences between cases and controls were analyzed by the Chi-square test.
  5. Age differences between cases and controls were analyzed by the t-test.