Variation in regulator of G-protein signaling 17 gene (RGS17) is associated with multiple substance dependence diagnoses

Table 2 Characteristics of SNPs in RGS20 and RGS17

ID	SNPs	Chromosome	Gene		Allele
ID	SNPs	Position (hg18)	Gene	Location	Allele	MAF (AAs)	MAF (EAs)
RGS17_1	rs9397578	153371201	RGS17	3' near gene	A/G	0.27 (A)	0.26 (A)
RGS17_2	rs7750874	153372161	RGS17	3' near gene	A/T	0.29 (A)	0.34 (A)
RGS17_3	rs503366	153375243	RGS17	Intron 4	C/T	0.47 (C)	0.49 (C)
RGS17_4	rs610614	153383477	RGS17	Intron 4	C/T	0.42 (C)	0.31 (C)
RGS17_5	rs545323	153387002	RGS17	Intron 4	C/T	0.05 (C)	0.33 (C)
RGS17_6	rs516557	153395551	RGS17	Intron 2	C/T	0.47 (T)	0.47 (C)
RGS17_7	rs9371276	153410854	RGS17	Intron 1	C/T	0.48 (T)	0.30 (C)
RGS17_8	rs1933258	153419500	RGS17	Intron 1	C/G	0.49 (G)	0.3 (C)
RGS17_9	rs9397585	153438568	RGS17	Intron 1	C/T	0.49 (C)	0.37 (C)
RGS17_10	rs685826	153452948	RGS17	Intron 1	C/T	0.46 (T)	0.44 (C)
RGS17_11	rs6931160	153472144	RGS17	Intron 1	C/G	0.50 (G)	0.44 (C)
RGS17_12	rs1281962	153473069	RGS17	Intron 1	C/G	0.24 (G)	0.46 (G)
RGS17_13	rs596359	153498746	RGS17	5' near gene	A/G	0.33 (G)	0.48 (G)
RGS20_1	rs1384797	54956481	RGS20	intron 1	A/G	0.40 (G)	0.02 (G)
RGS20_2	rs2220093	54963880	RGS20	intron 1	A/G	0.36 (A)	0.10 (G)
RGS20_3	rs1483537	54980301	RGS20	intron 1	A/G	0.35 (G)	0.01 (G)
RGS20_4	rs7824575	54984872	RGS20	intron 1	A/G	0.24 (G)	0.27 (A)
RGS20_5	rs2128821	55006166	RGS20	intron 1	C/G	0.42 (C)	0.26 (G)
RGS20_6	rs9298496	55018233	RGS20	intron 2	C/T	0.37 (C)	0.34 (C)
RGS20_7	rs6981243	55029044	RGS20	intron 3	A/C	0.42 (A)	0.41 (C)
RGS20_8	rs7009781	55035764	RGS20	downstream	C/T	0.27 (T)	0.17 (C)

Chromosome positions are based on Homo sapiens chromosome 6 genomic contig NT_025741.14 (RGS17) and chromosome 8 genomic contig NT_008183.18 (RGS20). MAF (AA), minor allele frequency in our African American (AA) sample; MAF (EA), minor allele frequency in our European Americans (EA) sample.

ISSN: 1744-9081