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Table 2 Serotonin transporter ( SLC6A4 ) single nucleotide polymorphisms (SNPs) investigated in suicidal attempters (SA) and non-suicidal (No SA) attempters with a schizophrenia diagnosis

From: Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia

SNP SNP localization Position   MAF Base Genotype counts Allele association Genotype association
       (SA/No SA)   OR   OR OR
    (no of bases)   (1/2) 1 1 1 2 2 2 P-value 2 vs 1 P-value 12 vs 11 22 vs 11
Rs1042173 3'-UTR 28525011   0.47 A/C 70/125 144/195 75/104 0.218 1.14 0.27 1.34 1.29
Rs4583306 Intron 8 28538715 13704 0.03 A/G 77/134 150/201 60/88 0.335 1.11 0.29 1.33 1.20
Rs140700 Intron 5 28543389 4674 0.08 C/T 243/348 43/79 2/0 0.560 0.89 0.11 0.80 2.26E9
Rs2020942 Intron 2 28546914 3525 0.39 C/T 108/157 135/201 44/68 0.777 0.97 0.94 0.99 0.93
Rs12150214 Intron 1 28550888 3974 0.17 G/C 213/301 67/117 10/8 0.735 0.95 0.23 0.81 1.72
Rs4251417 Intron 1 28551858 970 0.10 C/T 227/347 55/77 4/1 0.338 1.19 0.18 1.07 6.26
Rs16965628 Intron 1 28555425 3567 0.05 G/C 272/374 15/51 0/1 0.0009 (0.01) 0.39 0.004 (0.02) 0.40 3.92E-5
  1. The table shows nominal allele and genotype association results with gender and country as covariates.
  2. Chromosomal position, minor allele frequency (MAF), SNP-alleles (Base), genotype counts, P-values and odds ratios (OR) for allele and genotype association for the seven SNP markers are presented in the table. Global significant P-values are shown in parenthesis.