Figure 7

DRD4 percentage DNA methylation levels in CEPH transformed lymphoblastoid cell lines and post-mortem Mid-brain and Singular Temporal Gyrus tissue (STG). a) Average DRD4 DNA methylation levels plotted by rs936465 genotype b) DNA methylation levels across individual DRD4 CpG sites plotted by rs936465 genotype group. * = significant associations at the p < 0.05 level. Though arcsine transformed data were used in analyses, the true proportion of DNA methylation observed is plotted here. The one subject with available mid-brain DNA methylation data who was GG homozygous at rs936465 was combined with the heterozygotes for analyses.