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Table 4 Correlations between neuropsychological measures and Axial Diffusivity of white matter tracts in the Right Hemisphere across all study participants

From: Atlas-based white matter analysis in individuals with velo-cardio-facial syndrome (22q11.2 deletion syndrome) and unaffected siblings

Domain Measure Right Hemisphere
   Frontal/Temp Parietal/Occipital A/P Long Tracts Cer
   CGC SCR PTR PCR SLF IFO SCP
Memory & Attention Digit Span FW 0.23 0.20 0.25 0.17 0.16 0.25 0.36 *
  Digit Span BW 0.24 0.12 0.38 * 0.26 0.30 0.36 * 0.44 *
  Visual Span FW 0.42 * 0.38 * 0.29 0.48 ** 0.47 ** 0.48 ** 0.25
  Visual Span BW 0.38 * 0.24 0.25 0.51 0.57 ** 0.61 *** 0.29
  CVLT_List A, , Trials 1–5 0.18 0.17 0.29 0.36 * 0.38 * 0.25 0.26
Executive Function WCST Perseverative Error 0.29 0.29 0.37 * 0.48 ** 0.58 ** 0.48 ** 0.32
  BRIEF Behavioral Regulation −0.17 −0.31 −0.28 −0.40 * −0.48 ** −0.34 −0.17
  BRIEF Metacognition −0.22 −0.36 * −0.30 −0.45 ** −0.53 ** −0.41 * −0.18
Social Cognition BASC Social Skills 0.14 0.14 0.23 0.29 0.43 * 0.24 0.22
Socialization Vineland Soc Skills 0.17 0.22 0.27 0.38 * 0.54 ** 0.41 * 0.31
  SRS −0.24 −0.34 −0.27 −0.49 ** 0.41 * −0.44 * −0.27
Emotion Emotion Recognition 0.24 0.15 0.17 0.28 0.38 * 0.41 * 0.23
Psychiatric BASC Anxiety −0.13 −0.23 −0.19 −0.34 −0.39 * −0.22 −0.31
Symptoms BASC Atypicality −0.16 −0.38 * −0.26 −0.44 * −0.48 ** −0.35 * −0.23
  CGAS 0.11 0.29 0.31 0.44 * 0.57 ** 0.39 * 0.33
Overall Verbal IQ 0.44 * 0.24 0.46 ** 0.48 ** 0.60 *** 0.52 ** 0.47 **
Cognition Performance IQ 0.49 ** 0.37 * 0.45 ** 0.58 ** 0.63 *** 0.62 *** 0.47 **
  1. *p FDR  < 0.05.
  2. **p FDR  < 0.01.
  3. ***p FDR  < 0.001.
  4. The subset of WM tracts included in this table had significantly different AD between individuals with VCFS and unaffected siblings (p FDR  < 0.05). For abbreviations and further details, see the legend of Table 3.