Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate levels and neurocognition in non-smoking, active alcoholics

Table 3 NAA/Cr ratio measurements and WCST scores in alcoholics and controls

Parameter	Alcoholic group ( n = 49)	Control group ( n = 45)	t	df	P
Left Prefrontal GM	1.59 ± 0.13	1.66 ± 0.12	−2.59	92	0.011^a
Left Prefrontal WM	1.58 ± 0.12	1.70 ± 0.07	−6.03	80	<0.001^b
Left Parietal GM	1.53 ± 0.09	1.55 ± 0.07	−1.24	91	0.220
Left Parietal WM	1.56 ± 0.10	1.56 ± 0.06	−0.33	77	0.746
Cerebellar vermis	0.94 ± 0.06	0.94 ± 0.06	−0.07	90	0.946
		F = 8.12,v1 = 5,v2 = 86,P < 0.001^c
Number of corrects	30.37 ± 3.73	37.78 ± 2.37	−11.58	82	<0.001^b
Perseverative errors	11.49 ± 3.39	6.04 ± 2.44	8.87	92	<0.001^b
Random errors	6.18 ± 2.64	4.18 ± 1.34	4.70	72	<0.001^b
Categories completed	2.08 ± 1.59	4.93 ± 0.65	−11.52	65	<0.001^b
		F = 37.74,v1 = 4,v2 = 89,P < 0.001^d
		F = 17.18,v1 = 9,v2 = 82,P < 0.001^e

^a Value is statistically significant (P < 0.05).
^b Value is statistically significant (P < 0.001).
^c Alcoholic group was different from controls for the variables of NAA/Cr levels.
^d Alcoholic group was different from controls for the variables of WCST scores.
^e Alcoholic group was different from controls for the variables including all the NAA/Cr levels and WCST scores.

ISSN: 1744-9081