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Figure 2 | Behavioral and Brain Functions

Figure 2

From: Comparative study between bone marrow mononuclear fraction and mesenchymal stem cells treatment in sensorimotor recovery after focal cortical ablation in rats

Figure 2

MSCs and BMMCs promoted the same level of recovery. (A) Upper graph: sensorimotor function over time in the Cylinder Test. In all groups, the greater asymmetry was observed at PAD 2. Two-way ANOVA analysis revealed no significant interaction, but significant effect of the treatment. Thus, MSCs curve and BMMCs group curve were significantly closer to normal state (PAD 0) than the control group curve. Points in the graph mean mean±SEM. Lower graph: Data from each group was grouped and analyzed by ANOVA followed by a post-hoc analysis, which showed significant recovery in MSCs and BMMCs groups, but no significant difference between them. Bars mean mean±SEM. * = p < 0.05, *** = p < 0.001; Tukey. (B) Sensorimotor function over time in the Adhesive Test. Legend in (A) is valid in (B). In all groups, the lower level of contralateral preference was observed at PID 2. Two-way ANOVA analysis revealed a significant interaction and post-hoc analysis showed significant recovery in MSCs and BMMCs groups from the PAD 35 onwards. However, significant difference between them was found only at PAD 91. Points in the graph mean mean±SEM. * represents comparison among MSCs and control groups, # represents the comparison among BMMCs and control groups and Φ represents the comparison among MSCs and BMMCs groups. (* = p < 0.05; **, ## or ΦΦ = p < 0.01; *** or ### = p < 0.001; Tukey).

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