Skip to main content

Table 1 Demographics and clinical characteristics of Alzheimer’s disease study sample

From: Genetic association between APOE*4 and neuropsychiatric symptoms in patients with probable Alzheimer's disease is dependent on the psychosis phenotype

 

No APOE*4 alleles (n=348)

One APOE*4 allele (n=368)

Two APOE*4 alleles (n=74)

P*

Male, frequency (%)

111 (32%)

116 (32%)

32 (43%)

.131

Age at assessment, mean [SD]

78.1 [5.9]

76.2 [5.8]

72.8 [5.4]

<.001

Duration of illness (years)

3.7 [2.5]

4.2 [2.9]

3.9 [2.8]

.077

Education (years)

12.5 [3.1]

12.8 [3.0]

13.1 [2.7]

.208

Baseline MMSE

17.5 [5.8]

17.6 [5.2]

17.5 [5.8]

.960

Baseline CDR

1.31 [0.69]

1.29 [0.63]

1.24 [0.67]

.623

  1. *Chi-square tests for differences in gender by genotype, and ANOVA for differences in means across genotype for all other demographic measures.
  2. Abbreviations: APOE, apolipoprotein E; MMSE, Mini-Mental State Examination; CDR, Clinical Dementia Rating scale; ANOVA, analysis of variance.