Psychiatric symptoms of patients with primary mitochondrial DNA disorders

Table 3 Comparison of SCL-90-R, BDI-SF, HDRS and HAQ-DI scores of MT and HN patients

	MT group		HN group		t-value	df	D	p value (Raw)	p value (Adjusted)
Measured items	mean	SD	mean	SD
GSI	1.44	0.91	0.46	0.53	3.64	21	1.587	0.0015	0.0130*
Somatization	1.77	1.10	0.98	0.83	1.83	21	0.798	0.0817	0.0817
Obsessive-compulsive	1.65	1.04	0.47	0.68	3.99	21	1.743	0.0007	0.0079*
Interpersonal sensitivity	1.55	0.97	0.40	0.51	3.99	21	1.740	0.0007	0.0079*
Depression	1.90	1.21	0.75	1.03	3.12	21	1.362	0.0052	0.0309*
Anxiety	1.32	1.14	0.42	0.63	3.19	21	1.392	0.0044	0.0309*
Hostility	1.26	1.00	0.48	0.50	2.60	21	1.133	0.0169	0.0428*
Phobia	1.14	1.11	0.29	0.56	3.06	21	1.335	0.0060	0.0309*
Paranoia	1.42	1.05	0.28	0.39	3.81	21	1.665	0.0010	0.0101*
Psychoticism	0.92	0.60	0.13	0.24	5.65	21	2.465	<.0001	0.0002*
Additional items	1.48	0.96	0.43	0.66	3.66	21	1.599	0.0014	0.0130*
BDI-SF	12.85	8.33	4.40	5.36	3.18	21	1.386	0.0045	0.0309*
HDRS	15.62	8.62	7.30	5.52	2.67	21	1.166	0.0143	0.0428*
HAQ-DI	0.82	0.59	0.71	0.59	0.52	21	0.228	0.6076	0.6076

Abbr.: SCL-90-R Symptom Checklist-90-Revised; GSI global severity index; BDI Beck Depression Inventory-Short Form; HDRS Hamilton Depression rating Scale, HAQ-DI Stanford Health Assessment Questionnaire Disability Index. D: Cohen's d effect size, Adjusted_p: p values with Bonferroni-Holm correction. Asterisks refer to statistically significant differences (p ≤ 0.05) between the two groups.

ISSN: 1744-9081