Group | rs2234693 | rs9340799 | Frequencies | OR (95% CI) | p-value | Global haplotype association | ||
---|---|---|---|---|---|---|---|---|
Cases | Controls | All | ||||||
All | T | A | 0.478 | 0.620 | 0.550 | 1 | Â | < 0.0001 |
C | A | 0.323 | 0.187 | 0.253 | 0.45 (0.33 - 0.61) | < 0.0001 | ||
C | G | 0.070 | 0.191 | 0.133 | 1.94 (1.23 - 3.06) | 0.0046 | ||
T | G | 0.130 | 0.002 | 0.064 | 0.01 (0.00 - 0.10) | < 0.0001 | ||
Male | T | A | 0.473 | 0.654 | 0.563 | 1 | Â | < 0.0001 |
C | A | 0.294 | 0.195 | 0.244 | 0.47 (0.30 - 0.73) | 0.0009 | ||
C | G | 0.058 | 0.151 | 0.105 | 1.75 (0.83 - 3.69) | 0.14 | ||
T | G | 0.176 | 0.000 | 0.088 | 0.00 (−Inf - Inf) | 1 | ||
Female | T | A | 0.490 | 0.585 | 0.540 | 1 | Â | < 0.0001 |
C | A | 0.344 | 0.179 | 0.259 | 0.44 (0.28 - 0.68) | 0.0002 | ||
C | G | 0.090 | 0.232 | 0.163 | 2.04 (1.18 - 3.53) | 0.012 | ||
T | G | 0.076 | 0.004 | 0.037 | 0.04 (0.01 - 0.35) | 0.0035 |