Effect of chronic restraint stress on body weight gain. Rats subjected to restraint stress failed to gain weight (A and B). Differences in body weight gain were observed from day 7 between stressed and unstressed rats from both control and ω-3 groups, and from day 14 for animals from the vehicle groups (A). In contrast, unstressed rats gained weight throughout the study. ω-3: ω-3 supplementation. Data are represented as means ± SEM. An asterisk (*) indicates significant differences.