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Table 1 Body weight, body composition, and appetite of ziprasidone- and olanzapine-treated patients (n = 10 per group)

From: Effects of ziprasidone and olanzapine on body composition and metabolic parameters: an open-label comparative pilot study

  Ziprasidone start Ziprasidone end   Olanzapine start Olanzapine end   Ziprasidone change (%)a Olanzapine change (%)a  
Measure Median (IQR) Median (IQR) Pb Median (IQR) Median (IQR) Pb Median (IQR) Median (IQR) Pc
BW(kg) 58.75 (54.28, 61.68) 60.85 (56.40, 67.88) 0.168 57.70 (51.25, 65.90) 65.70 (56.73, 72.88) 0.005* 3.43 (0.61, 9.20) 10.35 (9.27, 14.65) 0.016*
BMI (kg/m2) 21.50 (19.20, 24.00) 22.35 (19.48, 25.18) 0.139 21.85 (17.90, 23.65) 23.95 (20.35, 26.53) 0.005* 4.09 (0.55, 10.20) 10.93 (9.02, 15.08) 0.019*
Waist to hip ratio 0.86 (0.83, 0.91) 0.84 (0.82, 0.94) 0.916 0.85 (0.81, 0.88) 0.87 (0.85, 0.93) 0.005* 0.00 (−0.01, 0.02) 3.62 (2.16, 5.10) 0.004*
LBM (kg) 44.65 (38.13, 48.30) 46.35 (42.48, 51.20) 0.028* 44.35 (40.23, 54.30) 47.70 (41.63, 54.25) 0.074 3.05 (1.36, 9.71) 3.78 (−2.41, 11.53) 0.821
Muscle mass (kg) 41.90 (35.80, 45.68) 43.55 (39.88, 49.00) 0.028* 41.75 (37.95, 51.55) 43.80 (39.20, 51.50) 0.074 3.01 (0.53, 9.67) 3.90 (−2.50, 7.40) 0.762
Fat mass (kg) 17.05 (7.58-21.88) 14.65 (8.40, 23.23) 0.721 13.00 (10.15, 15.73) 17.70 (12.05, 20.33) 0.017* 7.84 (−12.34, 28.88) 31.57 (20.15, 56.03) 0.049*
Appetite 5.00 (4.31, 6.44) 5.00 (3.38, 5.31) 0.212 5.00 (4.19, 5.25) 5.00 (4.69, 6.13) 0.399 −20.0 (−29.80, 5.00) 0.00 (−6.25, 39.34) 0.059
  1. IQR Interquartile Range, BW Body Weight, BMI Body Mass Index, LBM, LBM.
  2. a, posttreatment baseline baseline * 100; b,Wilcoxon signed rank test; c, Kruskal-Wallis H test; *, p < 0.05.