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Table 3 Genotype distributions of BDNF Val66Met

From: Functional Val66Met polymorphism of Brain-derived neurotrophic factor in type 2 diabetes with depression in Han Chinese subjects

Group

n

Genotype n (%)

Met allele frequency

Val/ Val

Val/Met

Met/Met

Met(A)(%)

HC

70

26(37.1)

33(47.1)

11(15.7)

39.3

NDDM

232

88(37.9)

108(46.6)

36(15.5)

38.8

DDM

64

15(23.4)

29(45.3)

20(31.3)

53.9

  1. Data expressed as frequency [n (%)], p value < 0.05 for statistical significance, chi-square analysis used to identify differences in genotype frequencies between groups. HC: Healthy control, NDDM: type 2 diabetes without depression group, DDM: type 2 diabetes with depression group.