Figure 2

SLAG(+) task performance. Original still shots (left) from Additional file 1 are accompanied by modifications using the “Glowing Edges” stylization function of Adobe Photoshop software (right), to enhance visualization of the mouse’s paws in relation to the wire lid. During the first descent, the mouse does not reach toward the wire lid (A) until it begins to become close (B), leading to obvious, sustained forepaw extension (C). Finally, the mouse is permitted to grasp the wire lid and remain on it for several seconds. The task is repeated with the mouse in opposite horizontal orientation. Upon the second descent, the mouse does not immediately reach toward the wire lid (D), but as it gets closer, the mouse twists its body around to reach (E), until an obvious, sustained, directed manner is observed (F). Finally, the mouse is permitted to grasp the wire lid as the test is completed.