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Table 2 Effects of the CNNM2 genotype and genotype-diagnosis interaction on GM volumes

From: The impact of the genome-wide supported variant in the cyclin M2 gene on gray matter morphology in schizophrenia

Brain regions R/L BA CS p values (peak) Talairach coordinates
     T FWE x y z
Non-risk minor allele carrier > Risk major allele homozygote
Inferior frontal Gyrus R 11/47 1306 4.96 0.0088 22 31 -20
Inferior frontal Gyrus L 47 437 4.66 0.031 -22 18 -22
Middle frontal Gyrus L 11 667 4.33 0.11 -24 38 -18
Posterior cingulate L 29 248 3.73 0.61 -7 -48 11
Non-risk minor allele carrier < Risk major allele homozygote
no suprathreshold clusters         
Genotype-diagnosis interaction
Superior temporal Gyrus L 22 598 4.23 0.16 -46 -20 1
  1. Abbreviations: R right; L left; BA Brodmann area; CS Cluster size; FWE family-wise error.
  2. All regions shown have nominal association at a voxel-level height threshold of uncorrectedp < 0.001 and a minimum clusters extent of 100 voxels. Significant results (FWE-correctedp < 0.05) are shown in bold face.