The female but not male rats with IAA-induced gastritis develop depression-like behavior. The sucrose preference test was used to measure depression. The sucrose preference correlated negatively with the depression state. IAA, iodoacetamide. Values are means ± S.E.M. *p < 0.05 was significantly different from control group of the same gender. N = 8 rats/male group, N = 6 rats/female group.