The IAA treatment causes changes in sex hormones in rats of either gender. (A) Plasma levels of 17ß-estradiol are decreased in female rats with IAA-induced gastritis. (B) Plasma levels of testosterone are increased in male rats with IAA-induced gastritis. IAA, iodoacetamide. Values are means ± S.E.M of six rats. *p < 0.05 was significantly different from control group of the same gender.