SNP | Allele | Alleles | Genotypes | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | 1 | 2 | 2 vs. 1 |  | Cases N (%) | Controls N (%) | Genotype 11 vs. 12+22 | Genotype 11+12 vs. 22 | |||||||
 |  |  | OR (95% CI) | P | 11 | 12 | 22 | 11 | 12 | 22 | P | OR (95% CI) | P | OR (95% CI) | P |
ADHD in general | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
rs4969239 | A | G | 1.10 (0.93-1.29) | 0.261 | 226 (42.6) | 233 (44.0) | 71 (13.4) | 423 (44.6) | 421 (44.4) | 104 (11.0) | 0.366 | Â | Â | Â | Â |
rs4969358 | A | C | 1.12 (0.97-1.31) | 0.135 | 97 (17.3) | 280 (49.8) | 185 (32.9) | 148 (15.6) | 452 (47.6) | 350 (36.8) | 0.284 | Â | Â | Â | Â |
rs6565531 | A | G | 1.05 (0.90-1.23) | 0.503 | 82 (14.6) | 252 (44.9) | 227 (40.5) | 146 (15.3) | 441 (46.3) | 366 (38.4) | 0.726 | Â | Â | Â | Â |
rs8079626 | A | G | 1.06 (0.91-1.23) | 0.482 | 84 (15.5) | 249 (45.9) | 209 (38.6) | 155 (16.3) | 444 (46.7) | 352 (37.0) | 0.819 | Â | Â | Â | Â |
rs3934492 | C | G | 1.16 (0.99-1.35) | 0.055 | 184 (33.4) | 273 (49.5) | 94 (17.1) | 297 (31.7) | 428 (45.6) | 213 (22.7) | 0.033 | 1.09 (0.86-1.35) | 0.490 | 1.43 (1.09-1.85) | 0.009 |
rs9901648 | A | G | 1.02 (0.87-1.20) | 0.811 | 249 (46.6) | 232 (43.4) | 53 (9.9) | 465 (49.1) | 374 (39.5) | 109 (11.5) | 0.283 | Â | Â | Â | Â |
rs4076037 | A | G | 1.11 (0.96-1.29) | 0.165 | 132 (24.5) | 272 (50.5) | 135 (25.0) | 267 (28.1) | 460 (48.5) | 222 (23.4) | 0.305 | Â | Â | Â | Â |
rs8066330 | C | T | 1.08 (0.93-1.26) | 0.289 | 146 (26.0) | 279 (49.6) | 137 (24.4) | 220 (23.2) | 496 (52.2) | 234 (24.6) | 0.444 | Â | Â | Â | Â |
rs4969385 | C | T | 1.27 (1.04-1.55) | 0.018 | 368 (67.6) | 153 (28.1) | 23 (4.2) | 681 (71.4) | 259 (27.1) | 14 (1.5) | 0.003 | 1.19 (0.95-1.50) | 0.129 | 2.96 (1.51-5.81) | 0.001 b |
Inattentive subtype | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
rs4969239 | A | G | 1.29 (1.06-1.58) | 0.010 | 103 (37.5) | 126 (45.8) | 46 (16.7) | 423 (44.6) | 421 (44.4) | 104 (11.0) | 0.015 | 1.35 (1.02-1.77) | 0.035 | 1.63 (1.12-2.38) | 0.010 |
rs4969358 | A | C | 1.21 (0.99-1.46) | 0.052 | 55 (18.9) | 146 (50.2) | 90 (30.9) | 148 (15.6) | 452 (47.6) | 350 (36.8) | 0.135 | Â | Â | Â | Â |
rs6565531 | A | G | 1.07 (0.89-1.30) | 0.474 | 37 (12.7) | 139 (47.6) | 116 (39.7) | 146 (15.3) | 441 (46.3) | 366 (38.4) | 0.535 | Â | Â | Â | Â |
rs8079626 | A | G | 1.05 (0.87-1.27) | 0.612 | 40 (14.0) | 140 (49.0) | 106 (37.1) | 155 (16.3) | 444 (46.7) | 352 (37.0) | 0.611 | Â | Â | Â | Â |
rs3934492 | C | G | 1.22 (1.01-1.48) | 0.039 | 104 (36.0) | 1396 (47.1) | 49 (17.0) | 297 (31.7) | 428 (45.6) | 213 (22.7) | 0.091 | 0.82 (0.63-1.09) | 0.171 | 0.70 (0.49-0.98) | 0.037 |
rs9901648 | A | G | 1.00 (0.82-1.23) | 0.985 | 130 (46.6) | 124 (44.4) | 25 (9.0) | 465 (49.1) | 374 (39.5) | 109 (11.5) | 0.239 | Â | Â | Â | Â |
rs4076037 | A | G | 1.18 (0.98-1.43) | 0.084 | 59 (21.0) | 153 (54.4) | 69 (24.6) | 267 (28.1) | 460 (48.5) | 222 (23.4) | 0.054 | Â | Â | Â | Â |
rs8066330 | C | T | 1.08 (0.89-1.30) | 0.412 | 77 (26.4) | 145 (49.7) | 70 (24.0) | 220 (23.2) | 496 (52.2) | 234 (24.6) | 0.526 | Â | Â | Â | Â |
rs4969385 | C | T | 1.27 (0.99-1.62) | 0.061 | 194 (68.3) | 76 (26.8) | 14 (4.9) | 681 (71.4) | 259 (27.1) | 14 (1.5) | 0.003 | 1.16 (0.87-1.54) | 0.318 | 3.48 (1.64-7.39) | 0.001 b |
Combined subtype | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
rs4969239 | A | G | 1.13 (0.91-1.41) | 0.281 | 114 (48.7) | 98 (41.9) | 22 (9.4) | 423 (44.6) | 421 (44.4) | 104 (11.0) | 0.497 | Â | Â | Â | Â |
rs4969358 | A | C | 1.06 (0.87-1.30) | 0.569 | 39 (15.7) | 125 (50.2) | 85 (34.1) | 148 (15.6) | 452 (47.6) | 350 (36.8) | 0.711 | Â | Â | Â | Â |
rs6565531 | A | G | 1.04 (0.84-1.28) | 0.732 | 41 (16.6) | 104 (42.1) | 102 (41.3) | 146 (15.3) | 441 (46.3) | 366 (38.4) | 0.502 | Â | Â | Â | Â |
rs8079626 | A | G | 1.08 (0.87-1.32) | 0.499 | 40 (17.2) | 98 (42.1) | 95 (40.8) | 155 (16.3) | 444 (46.7) | 352 (37.0) | 0.436 | Â | Â | Â | Â |
rs3934492 | C | G | 1.10 (0.90-1.35) | 0.341 | 74 (30.8) | 125 (52.1) | 41 (17.1) | 297 (31.7) | 428 (45.6) | 213 (22.7) | 0.103 | Â | Â | Â | Â |
rs9901648 | A | G | 1.03 (0.82-1.28) | 0.823 | 110 (47.2) | 98 (42.1) | 25 (10.7) | 465 (49.1) | 374 (39.5) | 109 (11.5) | 0.761 | Â | Â | Â | Â |
rs4076037 | A | G | 1.06 (0.87-1.30) | 0.553 | 66 (28.0) | 108 (45.8) | 62 (26.3) | 267 (28.1) | 460 (48.5) | 222 (23.4) | 0.624 | Â | Â | Â | Â |
rs8066330 | C | T | 1.07 (0.88-1.31) | 0.486 | 63 (25.4) | 122 (49.2) | 63 (25.4) | 220 (23.2) | 496 (52.2) | 234 (24.6) | 0.666 | Â | Â | Â | Â |
rs4969385 | C | T | 1.31 (1.01-1.71) | 0.042 | 158 (66.4) | 71 (29.8) | 9 (3.8) | 681 (71.4) | 259 (27.1) | 14 (1.5) | 0.060 | 1.26 (0.93-1.71) | 0.131 | 2.64 (1.13-6.17) | 0.040 |