BAIAP2 exhibits association to childhood ADHD especially predominantly inattentive subtype in Chinese Han subjects

Table 7 Haplotype analyses for 569 ADHD versus 957 controls

Haplotype		ADHD (n = 569)			ADHD-I (n = 295)			ADHD-C (n = 252)
Haplotype		χ²	Nominal P	Empirical P^c	χ²	Nominal P	Empirical P^c	χ²	Nominal P	Empirical P^c
Block2 ^a	GA↓	3.31	0.069	0.307	3.98	0.046	0.217	0.76	0.384	0.890
	CG	0.15	0.696	0.993	0.01	0.909	1.000	0.11	0.736	0.996
	CA↑	3.26	0.071	0.312	5.20	0.023	0.110	0.56	0.456	0.936
Block3 ^b	TC	1.11	0.291	0.781	0.66	0.419	0.902	0.49	0.484	0.948
	CC	0.49	0.482	0.937	0.33	0.561	0.967	0.63	0.427	0.916
	CT↑	5.44	0.019	0.097	3.47	0.062	0.274	3.96	0.047	0.215

^aHaplotype of block 2 coded by rs3934492 and rs9901648; ^bHaplotype of block 3 coded by rs8066330 and rs4969385; ^cEmpirical P value estimated on basis of 5,000 permutations; ↓: the frequency in ADHD cases was lower than that in controls; ↑: the frequency in ADHD cases was higher than that in controls. Nominal P values < 0.05 are indicated in bold.

ISSN: 1744-9081