Polymorphisms
|
Number and frequency (%)
|
---|
|
Male normal controls
|
Low score subgroup
|
High score subgroup
|
---|
rs4565946
|
84
|
25
|
87
|
CC
|
46 (54.76)
|
15 (60.00)
|
43 (49.43)
|
CT
|
33 (39.29)
|
6 (24.00)
|
29 (33.33)
|
TT
|
5 (5.95)
|
4 (16.00)
|
15 (17.24)
|
χ
2
| |
3.708
|
5.308
|
P
a
| |
0.157
|
0.070
|
CC + CT
|
79 (94.05)
|
21 (84.00)
|
72 (82.76)
|
TT
|
5 (5.95)
|
4 (16.00)
|
15 (17.24
|
χ
2
| |
2.568
|
5.273
|
P
b
| |
0.206
|
0.022
|
OR [95%CI]
| |
3.010 [0.742–12.205]
|
3.292 [1.139–9.513]
|
C
|
125 (74.40)
|
36 (72.00)
|
115 (66.09)
|
T
|
43 (25.60)
|
14 (28.00)
|
59 (33.91)
|
χ
2
| |
0.115
|
2.822
|
P
b
| |
0.734
|
0.093
|
OR [95%CI]
| |
1.130 [0.557–2.295]
|
1.491 [0.934–2.380]
|
rs4570625
|
84
|
25
|
87
|
TT
|
29 (34.52)
|
10 (40.00)
|
19 (21.84)
|
GT
|
40 (47.62)
|
9 (36.00)
|
41 (47.13)
|
GG
|
15 (17.86)
|
6 (24.00)
|
27 (31.03)
|
χ
2
| |
1.117
|
5.473
|
P
a
| |
0.572
|
0.065
|
TT + GT
|
69 (82.14)
|
19 (76.00)
|
60 (68.97)
|
GG
|
15 (17.86)
|
6 (24.00)
|
27 (31.03)
|
χ
2
| |
0.467
|
4.005
|
P
b
| |
0.494
|
0.045
|
OR [95%CI]
| |
1.453 [0.496–4.253]
|
2.070 [1.008–4.252]
|
T
|
98 (58.33)
|
29 (58.00)
|
79 (45.40)
|
G
|
70 (41.67)
|
21 (42.00)
|
95 (54.60)
|
χ
2
| |
0.002
|
5.724
|
P
b
| |
0.967
|
0.017
|
OR [95%CI]
| |
1.014 [0.535–1.922]
|
1.684 [1.097–2.583]
|
- a Pearson chi square test was used to calculate the p-values.
- bChi-square test was used to calculate the p-values. Fisher exact test was used when the sample size was <5.