Figure 2

Ultrastructure of neurons in hippocampus, TEM × 5000 (up) and × 20000 (down). 1: Control group, 2: Modeled group, 3: Treated group; Nm: Nuclear membrane, Ch: chromatin, Mi: Mitochondria, Go: Golgi apparatus, Vc: vacuoles caused by the dissolution of cytoplasm, Ly: Lysosome. In control group, neurons had distinct outline and cytoplasm with uniform chromatin; while the morphology of neurons in model group were irregular with uneven distribution of chromatin and dissolved cytoplasm vacuoles; the damage of neurons in treated group was milder than that in model group, and only some slightly gathered chromatin and a small amount of dissolved cytoplasm can be found.