Table 1 Effects of BPS on change of spatial learning and memory functions in aluminum overload rats
From: Beraprost sodium protects against chronic brain injury in aluminum-overload rats
N | Exploring time(s) | |||||
|---|---|---|---|---|---|---|
d 1 | d 2 | d 3 | d 4 | d 5 | ||
Control group | 13 | 60.5 ± 17.4 | 40.1 ± 10.8 | 25.0 ± 11.3 | 19.7 ± 11.9 | 11.1 ± 6.5 |
Al-overload group | 12 | 62.5 ± 15.7 | 49.1 ± 12.7 | 41.7 ± 19.1# | 33.0 ± 11.8# | 30.4 ± 17.7## |
BPS-6 group | 13 | 61.8 ± 15.5 | 39.6 ± 18.8 | 35.0 ± 16.6 | 27.4 ± 4.5 | 17.6 ± 8.5* |
BPS-12 group | 13 | 59.8 ± 18.3 | 36.3 ± 13.9 | 25.4 ± 6.9 | 21.1 ± 8.2* | 14.3 ± 6.4** |
BPS-24 group | 15 | 62.6 ± 15.8 | 39.3 ± 13.2 | 31.4 ± 11.9 | 23.8 ± 9.9* | 15.4 ± 8.7* |