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Figure 3 | Behavioral and Brain Functions

Figure 3

From: Anxiolytic and antidepressant profile of the methanolic extract of Piper nigrum fruits in beta-amyloid (1–42) rat model of Alzheimer’s disease

Figure 3

Effects of the methanolic extract of Piper nigrum fruits (50 and 100 mg/kg) on swimming time (a) and immobility time (b) in the Aβ (1–42)-treated rats during the 6 min period in the forced swimming test. Values are means + S.E.M. (n = 10 animals per group). For Turkey’s post hoc analysis - #Aβ (1–42) vs. Aβ (1–42) + P50: p < 0.0001 and ##Aβ (1–42) vs. Aβ (1–42) + P100: p < 0.001 (a), #Aβ (1–42) vs. Aβ (1–42) + P50: p < 0.001 and ##Aβ (1–42) vs. Aβ (1–42) + P100: p < 0.01 (b).

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