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Table 1 Categories of HIV-associated neurocognitive disorder according to Frascati criteria

From: DRD2 and DRD4 genes related to cognitive deficits in HIV-infected adults who abuse alcohol

  Neurocognitive statusa Functional statusb
Asymptomatic neurocognitive impairment 1 SD below the mean in 2 cognitive domains No impairment in activities of daily living
Mild neurocognitive impairment or disorder 1 SD below the mean in 2 cognitive domains Impairment in activities of daily living
HIV-associated dementia 2 SD below the mean in 2 cognitive domains Notable impairment in activities of daily living
  1. SD standard deviation
  2. aNeurocognitive testing should include an assessment of at least five domains, including attention–information processing, language, abstraction-executive, complex perceptual motor skills, memory (including learning and recall), simple motor skills, or sensory, perceptual skills
  3. bNo agreed measures exist for HIV-associated neurocognitive disorder criteria