DRD2 and DRD4 genes related to cognitive deficits in HIV-infected adults who abuse alcohol

Table 1 Categories of HIV-associated neurocognitive disorder according to Frascati criteria

	Neurocognitive status^a	Functional status^b
Asymptomatic neurocognitive impairment	1 SD below the mean in 2 cognitive domains	No impairment in activities of daily living
Mild neurocognitive impairment or disorder	1 SD below the mean in 2 cognitive domains	Impairment in activities of daily living
HIV-associated dementia	2 SD below the mean in 2 cognitive domains	Notable impairment in activities of daily living

SD standard deviation
^aNeurocognitive testing should include an assessment of at least five domains, including attention–information processing, language, abstraction-executive, complex perceptual motor skills, memory (including learning and recall), simple motor skills, or sensory, perceptual skills
^bNo agreed measures exist for HIV-associated neurocognitive disorder criteria

ISSN: 1744-9081