Skip to main content

Advertisement

Table 2 Unadjusted Spearman’s correlations

From: Serum concentrations of kynurenines in adult patients with attention-deficit hyperactivity disorder (ADHD): a case–control study

  Trp Kyn KTR HK KA XA AA HAA QA Vit. B2 Vit. B6 Cot ADHD status
All (N = 264)
 Age −0.24* −0.05 0.13* −0.13* −0.13* −0.26* 0.09 −0.27* −0.10 −0.04 −0.23* 0.26* 0.47*
 Sex 0.19* 0.18* 0.01 −0.11 0.21* 0.01 0.08 −0.04 −0.03 −0.14* 0.11 0.15* 0.04
 Trp   0.49* −0.46* 0.14* 0.34* 0.41* 0.10 0.34* 0.18* 0.17* 0.32* −0.13* −0.18*
 Kyn    0.48* 0.39* 0.48* 0.24* 0.36* 0.32* 0.58* 0.16* 0.19* −0.04 −0.09
 Vit. B2    −0.06 0.02 0.15* 0.23* 0.11 0.15* 0.27*   0.32* −0.13* −0.14*
 Vit. B6    −0.12 −0.12 0.22* 0.20* 0.03 0.24* 0.19*    −0.16* −0.12*
 Cotinine    0.05 −0.06 −0.08 −0.16* 0.02 −0.20* −0.03     0.52*
ADHD (N = 133)
 Age −0.30* −0.08 0.22* −0.26* −0.11 −0.31* 0.05 −0.27* −0.08 0.22* −0.16 −0.04  
 Sex 0.15 0.14 0.03 −0.04 0.08 0.03 −0.02 0.09 −0.00 −0.18* 0.09 0.13  
 Trp   0.55* −0.41* 0.21* 0.34* 0.48* 0.01 0.35* 0.32* 0.18* 0.40* −0.07  
 Kyn    0.46* 0.45* 0.50* 0.29* 0.32* 0.39* 0.64* 0.17 0.21* 0.07  
 Vit. B2    −0.03 −0.01 0.15 0.29* 0.10 0.15 0.30*   0.32* −0.13  
 Vit. B6    −0.17 −0.01 0.28* 0.26* −0.03 0.28* 0.24*    −0.27*  
 Cotinine    0.08 0.03 −0.11 −0.19* −0.03 −0.08 −0.01     
Control (N = 131)
 Age 0.10 0.10 −0.01 0.05 0.01 −0.03 0.10 −0.06 −0.10 −0.19* −0.24* 0.14  
 Sex 0.28* 0.25* −0.03 −0.19* 0.36* −0.01 0.20* −0.11 −0.08 −0.06 0.16 0.20*  
 Trp   0.41* −0.48* 0.04 0.31* 0.27* 0.24* 0.19* −0.02 0.13 0.21* 0.06  
 Kyn    0.55* 0.31* 0.46* 0.17 0.42* 0.16 0.50* 0.10 0.13 0.05  
 Vit. B2    −0.10 0.03 0.09 0.12 0.13 0.03 0.21*   0.33* 0.06  
 Vit. B6    −0.06 −0.26* 0.14 0.11 0.12 0.14 0.11    0.14  
 Cotinine    −0.02 −0.11 0.17 0.03 0.09 −0.10 −0.03     
  1. Significance: <0.05 ‘*’
  2. Trp tryptophan, Kyn kynurenine, KTR kynurenine/tryptophan ratio, HK 3-hydroxykynurenine, KA kynurenic acid, XA xanthurenic acid, AA anthranilic acid, HAA 3-hydroxyanthranilic acid, QA quinolinic acid, Cot cotinine