Fig. 3

Bar graphs depicting corticosterone levels in adult WT and Fgf8 ^+/neo mice in response to RS for a 15 or b 45 min. a RS for 15 min caused a significant rise in corticosteroid levels in WT (13.8 ± 0.8 μg/dL) and Fgf8 ^+/neo mice (17.8 ± 1.3 sem μg/dL) compared to NS WT (0.8 ± 0.4 sem μg/dL) and Fgf8 ^+/neo mice (0.6 ± 0.3 sem μg/dL). The rise in corticosteroid levels after 15 min of RS was significantly lower in WT than in Fgf8 ^+/neo mice. Differences in letters indicate p < 0.05. b RS for 45 min caused a significant rise in corticosteroid levels in WT (40.0 ± 2.5 μg/dL) and Fgf8 ^+/neo mice (47.7 ± 16.1 sem μg/dL) compared to NS WT (2.0 ± 1.4 sem μg/dL) and Fgf8 ^+/neo mice (1.9 ± 0.7 sem μg/dL). The rise in corticosteroid levels after 45 min of RS did not differ between WT and Fgf8 ^+/neo mice. Asterisk indicates p < 0.05 between animals treated with NS or RS conditions