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Fig. 4 | Behavioral and Brain Functions

Fig. 4

From: Fibroblast growth factor 8 regulates postnatal development of paraventricular nucleus neuroendocrine cells

Fig. 4

Photomicrographs depicting c-FOS immunoreactivity in adult NS a WT and b Fgf8 +/neo mice and RS c WT and d Fgf8 +/neo mice. Scale bar is 200 μm. e Bar graph depicting the number of c-FOS-IR cells in the adult PVN WT (1131.0 ± 113.3 sem) and Fgf8 +/neo (10,212.5 ± 142.6 sem) mice following 45 min of RS, which caused a significant increase in c-FOS-IR PVN cells compared to NS WT (76.0 ± 26.5 sem) and Fgf8 +/neo (56.5 ± 3.8 sem) mice (p < 0.001). However, two-way ANOVA analysis showed no significant genotypic effect (p = 0.5) or interaction between RS and genotype (p = 0.6). The difference in letters indicates a significance of p < 0.05

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