Attention deficit hyperactivity disorder: genetic association study in a cohort of Spanish children

Table 1 Description of the 34 polymorphisms analysed within 18 genes for ADHD

Gene	Description	Variant	Reference
SLC6A2	Norepinephrine transporter	rs28386840^a	[19]
SLC6A2	Norepinephrine transporter	r5569^c	[5]
ADRA2A	Adrenergic receptor alpha 2A	rs1800544^a	[5]
ADRA2A	Adrenergic receptor alpha 2A	rs553668^e	[5]
SLC6A3	Dopamine transporter	rs2550948^b	[22]
		rs2652511^b	[22]
		rs11564750^a	[22]
		3′UTR VNTR^e	[5]
		Intron8 VNTR^d	[5]
DRD2	Dopamine receptor D2	rs1800497^f	[21]
DRD4	Dopamine receptor D4	rs3758653^a	[20]
		Exon3 VNTR^c	[21]
		Promoter duplication^b	[21]
COMT	Catechol-O-methyltransferase	rs4680^c	[5]
COMT	Catechol-O-methyltransferase	rs4818^c	[50]
DDC	Dopa decarboxylase	rs6592961^d	[51]
SLC6A4	Serotonin transporter	Promoter VNTR^b	[5]
SLC6A4	Serotonin transporter	Intron2 VNTR^d	[5]
HTR2A	Serotonin-2A receptor	rs7322347^d	[51]
HTR2C	Serotonin-2C receptor	rs6318^c	[52]
SLC9A9	Glycine transporter	rs9810857^f	[53]
GRM7	Glutamate receptor, metabotropic 7	rs3792452^d	[54]
SNAP25	Synaptosomal-associated protein 25kDA	rs3746544^e	[5]
CDH13	Cadherin 13	rs6565113^d	[20]
GFOD1	Glucose-fructose oxidoreductase domain containing 1	rs552655^d	[20]
STS	Steroid sulfatase	rs12861247^d	[55]
STS	Steroid sulfatase	rs17268988^d	[55]
FADS2	Fatty acid desaturase 2	rs498793^d	[31]
LPHN3	Latrophilin 3	rs1397548^c	[17]
		rs2305339^d	[17]
		rs6551655^d	[17]
		rs1868790^d	[24]
		rs6813183^d	[24]
		rs6858066^d	[24]

Position in the gene: ^aupstream gene variant, ^b promoter variant, ^c exon variant, ^d intron variant, ^e 3′UTR variant, ^f downstream gene variant

ISSN: 1744-9081