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Table 1 Convergent gray matter decreases associated with chronic smoking: cluster coordinates

From: Chronic cigarette smoking is linked with structural alterations in brain regions showing acute nicotinic drug-induced functional modulations

Cluster Region Volume X Y Z
Nonsmokers > smokers
 1 Thalamus (lateral posterior nucleus) R 592 16 −22 14
 2 dmPFC (BA 6) (superior frontal gyrus) R 576 16 24 52
 3 vmPFC (BA10) (superior frontal gyrus) L 568 −8 56 −4
 4 vlPFC (BA 10) (middle frontal gyrus) R 480 32 46 4
 5 dmPFC (BA 8) (medial frontal gyrus) R 480 10 40 36
 6 Parahippocampal gyrus L 432 −20 −34 0
 7 mPFC (BA10) (medial frontal gyrus) R 416 12 58 8
 8 Medial OFC (BA 11) B 384 2 34 −20
 9 mPFC (BA10) (medial frontal gyrus) L 376 −14 58 8
 10 Cerebellum (dentate) R 368 14 −58 −20
 11 Insula (BA 13) L 368 −40 8 10
 12 Thalamus (medial dorsal nucleus) B 360 2 −18 4
  1. Numbering corresponds to brain regions shown in Fig. 1. Coordinates (X, Y, Z) of the clusters’ peak voxels are reported in Talairach space. Volume is mm3
  2. B bilateral, R right, L left, BA Brodmann area, OFC orbitofrontal cortex, vmPFC ventromedial prefrontal cortex, vlPFC ventrolateral prefrontal cortex, dmPFC dorsomedial prefrontal cortex, mPFC medial prefrontal cortex