Association between C3435T polymorphism of MDR1 gene and the incidence of drug-resistant epilepsy in the population of Polish children

Table 3 Distributions of TT, CT and CC genotypes and T and C alleles in C3435T polymorphism of MDR1 gene in the group of children with drug-resistant epilepsy and in the group of healthy children

	Children with drug-resistant epilepsy (n = 106)		Healthy children (n = 98)		OR (95 % CI^a)^b	p ^c
	Number	(%)	Number	(%)	OR (95 % CI^a)^b	p ^c
CC	35	33	16	16	1.00 Ref.^d
CT	39	37	37	38	0.48 (0.23–1.01)	0.079
TT	32	30	45	46	0.33 (0.15–0.68)	0.005
C	109	51	69	35	1.00 Ref.
T	103	49	127	65	0.53 (0.33–0.85)	0.012

^aCrude odds ratio (OR), 95 % CI confidence interval at 95 %
^bAdjusted for age and use of variety of drugs
^cfor the test of χ² conformity with the distribution predicted by the Hardy–Weinberg law
^dReference group—wild type of allele

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