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Table 3 Distributions of TT, CT and CC genotypes and T and C alleles in C3435T polymorphism of MDR1 gene in the group of children with drug-resistant epilepsy and in the group of healthy children

From: Association between C3435T polymorphism of MDR1 gene and the incidence of drug-resistant epilepsy in the population of Polish children

  Children with drug-resistant epilepsy (n = 106) Healthy children (n = 98) OR (95 % CIa)b p c
Number (%) Number (%)
CC 35 33 16 16 1.00 Ref.d  
CT 39 37 37 38 0.48 (0.23–1.01) 0.079
TT 32 30 45 46 0.33 (0.15–0.68) 0.005
C 109 51 69 35 1.00 Ref.  
T 103 49 127 65 0.53 (0.33–0.85) 0.012
  1. aCrude odds ratio (OR), 95 % CI confidence interval at 95 %
  2. bAdjusted for age and use of variety of drugs
  3. cfor the test of χ2 conformity with the distribution predicted by the Hardy–Weinberg law
  4. dReference group—wild type of allele